Bioidentical Hormones do not Raise Stroke Risk. News. Target) A large new study from France, published in an American Heart Association journal last spring, shows that bioidentical hormones do not raise the risk of stroke in menopausal women. While it has been well established over the past decade that menopausal women who use synthetic hormone replacement therapy (HRT) such as Prem. Pro have a significantly higher risk of stroke, there has been little safety data for bioidentical hormones. The French E3. N research, which is following 1. Bioidentical hormones have the same molecular structure as those made by the human body, while synthetic hormones are not found in nature.
Study: Different Hormone Therapy Formulations May Pose Different Risks for Heart Attack and Stroke. Vivelle-Dot is a patch that contains the estrogen hormone. Women`s Health Initiative (WHI), the British Million Women Study, and the French E3. N study, all published over the past decade. The French E3. N study is unique in that it provides valuable safety data for users of bioidentical hormones, most recently on estrogen, progesterone and the risk of stroke and blood clots. The most common kind of hormone replacement therapy used by French women is a combination of estradiol patch or gel, and oral progesterone - - both bioidentical hormones. The WHI study found that users of the hormone replacement drug Prem. Pro had a 4. 1% higher risk of stroke, so investigators of the French E3. N study examined the stroke risk factors for bioidentical hormones to find out if there is a difference. Prem. Pro is made from an estrogen- like extract of a pregnant mare`s urine (Premarin) and a synthetic progesterone or progestin called Provera. The latest release of information from the French E3. N examined the risk of stroke among women using oral (pill) estrogen, transdermal estrogen (patch or gel), different kinds of progestins, and progesterone. Bottom line, estrogen patches and gels are much safer than estrogen pills, and progesterone is safer than any of the progestins. In fact, women using estrogen patches and progesterone (in pill form) had a slightly lower risk of stroke compared to women not using any type of hormone replacement. The study measured estradiol and progesterone levels in 1. The stroke group as a whole had lower progesterone levels than the control group, and a significantly lower progesterone to estrogen ratio. Now, women who use bioidentical hormones have some assurance that their risk of stroke and blood clots is not increased. Jul 1. 7; 2. 88(3): 3. February, 2. 01. 0. May Not Tell You About Menopause with Dr. John Lee, and Prescription Alternatives. Virginia is currently editor of the Virginia Hopkins Health Watch newsletter, at http: //www.
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